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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HEATR1
All Species:
12.73
Human Site:
S1752
Identified Species:
21.54
UniProt:
Q9H583
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H583
NP_060542.4
2144
242370
S1752
K
N
T
S
E
L
V
S
S
E
V
Y
L
L
S
Chimpanzee
Pan troglodytes
XP_001156974
2144
242420
S1752
K
N
T
S
E
L
V
S
S
E
V
Y
L
L
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536334
2141
242568
S1749
K
N
T
S
E
L
L
S
G
E
V
Y
L
L
S
Cat
Felis silvestris
Mouse
Mus musculus
NP_659084
2143
242053
H1751
K
S
T
S
E
L
V
H
S
E
V
C
L
L
S
Rat
Rattus norvegicus
NP_001101888
2143
241191
R1751
K
S
T
S
E
L
V
R
S
E
V
C
L
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422958
2155
244590
S1763
K
N
K
K
E
L
I
S
N
E
I
Y
L
L
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q7SY48
2159
242032
N1755
K
E
R
K
D
L
L
N
N
E
I
Y
L
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VM75
2096
237201
A1699
K
E
Q
V
H
Q
M
A
S
L
K
Q
G
P
D
Honey Bee
Apis mellifera
XP_393800
2028
231830
V1622
E
D
H
C
H
Q
G
V
P
D
I
I
V
I
S
Nematode Worm
Caenorhab. elegans
Q23495
1650
185210
G1287
G
S
Q
T
S
G
F
G
S
K
T
G
I
H
H
Sea Urchin
Strong. purpuratus
XP_794611
1635
181917
G1272
R
K
L
G
K
M
E
G
R
H
T
I
V
P
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C8Z4
2001
224001
G1618
G
F
L
N
P
H
L
G
D
I
M
K
I
M
V
Baker's Yeast
Sacchar. cerevisiae
P42945
1769
200063
G1406
A
I
L
L
L
F
A
G
L
I
K
R
I
P
S
Red Bread Mold
Neurospora crassa
Q7RZM8
1788
196873
Q1425
A
F
M
A
A
L
A
Q
H
I
P
Y
M
I
S
Conservation
Percent
Protein Identity:
100
99.5
N.A.
89.7
N.A.
83.8
84.9
N.A.
N.A.
65.5
N.A.
54.5
N.A.
28.6
30.5
21.1
24.4
Protein Similarity:
100
99.8
N.A.
95
N.A.
92.1
92.7
N.A.
N.A.
80.5
N.A.
73
N.A.
49.4
50.8
38.9
43.2
P-Site Identity:
100
100
N.A.
86.6
N.A.
80
80
N.A.
N.A.
66.6
N.A.
46.6
N.A.
13.3
6.6
6.6
0
P-Site Similarity:
100
100
N.A.
93.3
N.A.
86.6
86.6
N.A.
N.A.
86.6
N.A.
80
N.A.
26.6
46.6
33.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.4
21.2
23
Protein Similarity:
N.A.
N.A.
N.A.
43.4
40.2
42.2
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
20
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
13.3
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
0
8
8
0
15
8
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
15
0
0
0
% C
% Asp:
0
8
0
0
8
0
0
0
8
8
0
0
0
0
8
% D
% Glu:
8
15
0
0
43
0
8
0
0
50
0
0
0
0
0
% E
% Phe:
0
15
0
0
0
8
8
0
0
0
0
0
0
0
0
% F
% Gly:
15
0
0
8
0
8
8
29
8
0
0
8
8
0
0
% G
% His:
0
0
8
0
15
8
0
8
8
8
0
0
0
8
8
% H
% Ile:
0
8
0
0
0
0
8
0
0
22
22
15
22
15
0
% I
% Lys:
58
8
8
15
8
0
0
0
0
8
15
8
0
0
0
% K
% Leu:
0
0
22
8
8
58
22
0
8
8
0
0
50
50
0
% L
% Met:
0
0
8
0
0
8
8
0
0
0
8
0
8
8
0
% M
% Asn:
0
29
0
8
0
0
0
8
15
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
8
0
0
0
8
0
8
0
0
22
0
% P
% Gln:
0
0
15
0
0
15
0
8
0
0
0
8
0
0
0
% Q
% Arg:
8
0
8
0
0
0
0
8
8
0
0
8
0
0
0
% R
% Ser:
0
22
0
36
8
0
0
29
43
0
0
0
0
0
72
% S
% Thr:
0
0
36
8
0
0
0
0
0
0
15
0
0
0
8
% T
% Val:
0
0
0
8
0
0
29
8
0
0
36
0
15
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
43
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _